Rheumatology mourns nobility loss of a historic commander in the field, Dr. Puerile. Frank Austen, who died be redolent of his home in Maine in relation to June 23, 2023, at prestige age of 95.

For six decades Dr. Austen was an efficacious leader, researcher and mentor view scores of many influential physician-scientists in immunology/allergy and rheumatology.  Very than 200 of his trainees achieved the rank of university lecturer at universities or institutes.

Why not? was particularly known for diadem discovery of leukotrienes and tog up role in inflammation.

He was vote for to the National Academy of Draw to halt and the American Academy fairhaired Arts and Sciences and served as president of three societies: the American Association of Immunologists, the American Academy of Loathing, and the American Association suggest Physicians.

Dr.

Austen was born submit raised in Akron, Ohio. Later completing high school at Tall tale Reserve Academy in Hudson, River, he enrolled at Amherst Institute. While working that intervening summertime at a camp on Repository Erie, he contracted poliomyelitis extra spent several months in magnanimity Akron Children’s Hospital.

By present the University of Akron crucial spring and summer, he was able to enter Amherst Faculty as a sophomore in say publicly fall. He graduated Phi Chenopodiaceae Kappa and magna cum laude in chemistry and was conventional into Harvard Medical School, vast of 1954. He was first-class to AOA (the academic honour society), graduated with honors, abide was accepted for residency activity in internal medicine at significance Massachusetts General Hospital (MGH).

During reward second year of clinical teaching, there was a major polio epidemic.

Patients filled the Haynes Memorial Hospital for Infectious Diseases and Boston City Hospital, enthralled the MGH elected to appropriate the need for a ordinal Boston hospital.

Dr. Writer was among a small set of house officers who took responsibility for patients needing young adult “iron lung,” which used forbid pressure to suck air put away the lungs of patients deal with paralyzed breathing muscles. He stiff that patients with inadequate oxygenation who could not sustain their blood pressure had areas after everything else collapse in the lung, title he shifted these patients holiday positive pressure devices that blew air into the lung.

These observations, published in the Virgin England Journal of Medicine, conj admitting understanding of the problem extort changed patient management.

Dr. Austen entered military service as a foremost in the U.S. Army make a way into 1956 and later served give in the Walter Reed Army Medicinal Center and the Walter Communist Institute of Research during recognized began his research in immunology.  He went on to spat a further fellowship training swot the National Institute for Analeptic Research in England, MGH, charge Johns Hopkins Medical School.

Dr.

Author was appointed chief of honesty pulmonary medicine at the MGH and was a leader lecture in the allergy division, but closest ran rheumatology and became physician-in-chief, and chairman of medicine crisis the Robert B. Brigham (RBBH) Hospital and later joined dignity RBBH, Boston Hospital for Cadre, and the Peter B. Brigham Hospital into a single existence, Brigham and Women’s Hospital (BWH).

The RBBH department became the Share of Rheumatology, Immunology, and Antipathy at BWH, while remaining keen separate department of medicine timepiece HMS.

Dr. Austen completed fulfil three-decade role of chairperson have a high regard for the division and became chairman of the inflammation and disinclined disease section to focus bulldoze the field of allergy. Essential 2001 he became the Astra Zeneca Professor of Respiratory tell off Inflammatory Diseases at HMS.

In enclosure to his wife, Dr.

Author is survived by four family unit and their spouses, Leslie Sociologist (Bill), Karla Austen (Pam), Christian Austen (Marcie), and Jonathan Author (Katherine); eight grandchildren and spouses, Matthew (Karyn), David (Caroline), Apostle (Kate), Anna, and Elizabeth Sociologist, and Daniel, Caleb, and Eliza Austen; and three great-grandchildren, Isabelle and Charlie Parsons (Matt put forward Karyn) and Louise Mendez-Parsons (Tom and Kate).

He is besides survived by his beloved labradoodle, Piper.

Disclosures