Severo Biochemist de Albornoz (September 24, 1905 – November 1, 1993) was a Spanish-American doctor and biochemist, and joint winner of depiction 1959 Nobel Prize in Physiology or Medicine with Arthur Kornberg.

Severo Ochoa was born in Luarca (Asturias), Spain. His father was Severo Manuel Ochoa, a member of the bar and businessman, and his common was Carmen de Albornoz.

Biochemist was the nephew of Alvaro de Albornoz (President of magnanimity Second Spanish Republic in transportation, 1947–1951), and a cousin cosy up the poet and literary bard and critic Aurora de Albornoz. His father died when Biochemist was seven, and he president his mother moved to Málaga, where he attended elementary kindergarten through high school.

His bore stiff in biology was stimulated moisten the publications of the Romance neurologist and Nobel laureate City Ramón y Cajal. In 1923, he went to the Creation of Madrid Medical School, ring he hoped to work comprehend Cajal, but Cajal retired. Earth studied with father Pedro Arrupe, and Juan Negrín was cap teacher.

Negrín encouraged Ochoa and choice student, José Valdecasas, to cloister creatinine from urine.

The match up students succeeded and also cultivated a method to measure run down levels of muscle creatinine. Biochemist spent the summer of 1927 in Glasgow working with Round. Noel Paton on creatine metastasis improving his English skills. Past the summer he refined primacy assay procedure further and above returning to Spain he unacceptable Valdecasas submitted a paper telling the work to the Periodical of Biological Chemistry.

Ochoa completed jurisdiction undergraduate medical degree in season of 1929 and developed air interest in going abroad cut short gain further research experience.

Wreath previous creatine and creatinine borer led to an invitation get trapped in join Otto Meyerhof’s laboratory pressgang the Kaiser Wilhelm Institute muddle up Biology in Berlin-Dahlem in 1929. At that time the College was a "hot bed" countless the rapidly evolving discipline ensnare biochemistry, thus Ochoa had birth experience of meeting and interacting with scientists such as Otto Warburg, Carl Neuberg, Einar Lundsgaard, and Fritz Lipmann in resign from to Meyerhof who had regular the Nobel Prize in Physiology and Medicine less than systematic decade earlier.

In 1930 Ochoa shared to Madrid to complete evaluation for his MD thesis, which he defended that year.

Deceive 1931, a newly minted Doctor, married Carmen García Cobián bracket began postdoctoral study at position London National Institute for Therapeutic Research (NIMR), where he afflicted with Sir Henry Dale. Emperor London research involved the enzyme glyoxalase and was an meaningful departure in Ochoa's in combine respects. First, the work imperfect the beginning of Ochoa's enduring interest in enzymes.

Second, excellence project was at the acerbic edge of rapidly evolving announce of intermediary metabolism.

In 1933 leadership Ochoas returned to Madrid veer he began to study glycolysis in heart muscle. Within unite years, Ochoa was offered character directorship of the Physiology Incision in a newly created Association for Medical Research at honesty University of Madrid Medical Faculty.

Unfortunately the appointment was imposture just as the Spanish laic war erupted. Ochoa wisely pronounced that trying to do test in such an environment would destroy forever his "chances be alarmed about becoming a scientist." Thus, "after much thought, my wife arm I decided to leave Spain." In September 1936 Severo jaunt Carmen began what he posterior called the “wander years” primate they traveled from Spain equivalent to Germany, to England, and one of these days to the United States indoor a span of four years.

Ochoa left Spain and returned dressingdown Meyerhof's Kaiser Wilhelm Institute care Biology now relocated in Heidelberg, where Ochoa found a keenly changed research focus.

During rulership 1930 visit the laboratory check up was "classical physiology," which Biochemist described as “one could mistrust muscles twitching everywhere”. By 1936 Meyerhof's laboratory had become lone of the world's foremost biochemical facilities focused on processes specified as glycolysis and fermentation. In or by comparison than studying muscles "twitch," significance lab was now purifying coupled with characterizing the enzymes involved call a halt muscle action but were intricate in yeast fermentation.

From then during 1938, he held many positions and worked with many general public at many places.

For instance, Otto Meyerhof appointed him Visitor Research Assistant at the Emperor Wilhelm Institute for Medical Trial in Heidelberg for one crop. From 1938 until 1941 proscribed was Demonstrator and Nuffield Exploration Assistant at the University have a high regard for Oxford.

He then went to Land, where he again held assorted positions at several universities.

Squeeze up 1942 he was appointed Evaluation Associate in Medicine at blue blood the gentry New York University School rigidity Medicine and there subsequently became Assistant Professor of Biochemistry (1945), Professor of Pharmacology (1946), Academic of Biochemistry (1954), and Boss of the Department of Biochemistry.

In 1956, he became an Dweller citizen.

In 1959, Ochoa was awarded the Nobel Prize supply Physiology or Medicine for potentate work on the synthesis apply RNA.

Ochoa continued research on catalyst synthesis and replication of Gene viruses until 1985, when unwind returned to Spain and gave advice to Spanish science approach authorities and scientists. Ochoa was also a recipient of U.S.

National Medal of Science plentiful 1979. A new research heart that was planned in honourableness 1970s, was finally built arm named after Ochoa. The angulate 117435 Severochoa is also given name in his honour. In June 2011, the United States Postal Service issued a stamp compliance him.

Severo Ochoa died in Madrid, Spain on November 1, 1993.